Wednesday, May 6, 2020

The Cell Theory Of Aging - 1813 Words

Introduction Every day we naturally lose skin and blood cells throughout our body; however, these cells are replaced through the proliferation and differentiation of stem cells found in pools throughout our bodies. Stem cells are found in most adult mammalian tissues, where they maintain normal tissue homeostasis and participate in tissue repair and regeneration in response to damage (Lui Rando 2011). The physiological process of aging may be the result of stem cell loss and a decline in the homeostatic and regenerative capacity of all tissues and organs (Lui Rando 2011). In fact, the stem cell theory of aging proposes that as we age, we fail to replenish the unique pool of stem cells. Consequently, this prevents us from replacing lost, differentiated cells and results in the inability to maintain and repair damaged tissues or organs. Therefore, it is important to understand the molecular mechanisms involved in the loss of stem cell function and find plausible solutions for treating age-related diseases. There are two classes of stem cells: embryonic stem cells and adult (or somatic) stem cells — this research will focus on the latter. Adult stem cells (ASC) are undifferentiated cells that can proliferate and differentiate into multipotent cells. Multipotent cells have the ability to give rise to multiple tissue types but are limited in their ability to indefinitely divide. Unlike embryonic stem cells (ESC), which are pluripotent and have the ability to divideShow MoreRelatedAging And The Aging Process1669 Words   |  7 Pages Aging, it’s something that as a species of life on this planet we are predisposed to and its results are an inevitable factor that effects our bodies in several ways, from cataracts development to the progression of memory issues from such diseases as Alzheimer’s or Huntington’s. 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